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. Author manuscript; available in PMC: 2015 Jan 16.
Published in final edited form as: Cell Rep. 2013 Dec 27;6(1):231–244. doi: 10.1016/j.celrep.2013.11.044

Figure 4. Functional Significance of 5-hmC Gains.

Figure 4

(A) Total number of gained 5-hmC peaks between days 0 and 3 (days 0–3, white), 3 and 7 (days 3–7, hatched), and 7 and 10 (days 7–10, striped) with respect to relative position to annotated gene elements.

(B) Relative number of 5-hmC peaks from (A) normalized to the base pair lengths of each element.

(C) Comparison of the normalized 5-hmC reads surrounding the TSS, indicated by a vertical dotted line, ±1,000 bp for all known annotated genes at day 0 (left) versus day 10 (right), plotted by the Metaseq suite (Dale, 2013).

(D) Percentage of the overlap among publicly available GATA1, GATA2, and KLF1 ChIP-seq data (Fujiwara et al., 2009; Kang et al., 2012; Tallack et al., 2010) and 5-hmC gained peaks over days 0–3 (white), 3–7 (hatched), and 7–10 (striped) time points with significance (p ≤ 10–5).

See also Figure S4.