. Author manuscript; available in PMC: 2015 Apr 30.

Published in final edited form as: Stat Med. 2013 Dec 16;33(9):1600–1618. doi: 10.1002/sim.6067

Table 1.

Powers and Type I Errors for the Sequential Meta-Design in Figure 1

(φ₀₁, φ₀₂)	a₀	Sample Size per Group for Trial 9
		n₉ = 2500		n₉ = 2750		n₉ = 3000		n₉ = 3250

		Power	Type I Error	Power	Type I Error	Power	Type I Error	Power	Type I Error
(0.97, 0.97)	0	0.7093	0.0492	0.7244	0.0488	0.7529	0.0483	0.7695	0.0478
	0.0050	0.7310	0.0536	0.7465	0.0515	0.7724	0.0511	0.7893	0.0520
	0.0150	0.7565	0.0607	0.7693	0.0582	0.7915	0.0567	0.8109	0.0584
	0.0215	0.7644	0.0640	0.7765	0.0610	0.7990	0.0592	0.8193	0.0604
	0.0250	0.7688	0.0648	0.7798	0.0624	0.8023	0.0614	0.8208	0.0618

(0.98, 0.96)	0	0.7365	0.0498	0.7506	0.0508	0.7751	0.0487	0.7968	0.0487
	0.0050	0.7555	0.0539	0.7702	0.0544	0.7934	0.0509	0.8145	0.0520
	0.0150	0.7779	0.0604	0.7913	0.0602	0.8148	0.0570	0.8333	0.0572
	0.0215	0.7845	0.0635	0.7996	0.0619	0.8205	0.0608	0.8394	0.0606
	0.0250	0.7881	0.0640	0.8019	0.0637	0.8251	0.0626	0.8404	0.0625

(0.98, 0.97)	0	0.6983	0.0404	0.7139	0.0424	0.7443	0.0400	0.7608	0.0398
	0.0050	0.7191	0.0450	0.7358	0.0452	0.7622	0.0433	0.7805	0.0426
	0.0150	0.7449	0.0502	0.7604	0.0510	0.7817	0.0480	0.8034	0.0478
	0.0215	0.7537	0.0527	0.7693	0.0525	0.7892	0.0505	0.8101	0.0502
	0.0250	0.7568	0.0532	0.7703	0.0535	0.7935	0.0510	0.8132	0.0513