Table 2. Amino acid mutations within surface protein of patient groups, arranged by immune epitopes.

Amino Acid Change	Nucleotide Mutation	MHR Regain		CTL Epitope			Cryptogenic Cirrhosis
		100-160	208	207	206	30	aa Position	Sample Code
			I	S	Y	Q	Wild type
	T213A						2
	C465T						4
	C465T						9
Y134F, S207R, I208T	C345T, A401T, C618T, A619C, C623T	Y134F	T	R			11
Y134F, S207R	T345C, A401T, C618T, A619C	Y134F		R			12
M103R, I110F, W201R, S204R	T308G, A328T, A342C, A366G, C465T, T601C, A610C	M103R, I110F					13
Q30K, Y134F, S207R	C88A, T345C, A401T, C618T, A619C	Y134F		R		K	14
	T213A						15
							16
Y134F, S207R	C345T, A401T, C414T, C618T, A619C	Y134F		R			17
							26

Amino acids are described by single-letter codes and numbered from the beginning of the surface protein. Only positions at which changes occurred are shown, so relative proportion of epitopic to non-epitopic areas is skewed in favor of regions where substitutions occurred.