Table 1.
Characteristics of IPAA patients by age. Except where indicated otherwise, data are median (range) or n (%) values.
| IPAA childhood (n = 12) | IPAA adulthood (n = 24) | P | |
|---|---|---|---|
| Age, years | 12 (5–16) | 33.5 (29–48) | <0.0001 |
| BMI, kg/m2 | 18 (15–23) | 21.5 (17–28) | 0.09 |
| Sex (male/female), n | 5/7 | 11/13 | >0.99 |
| Steroids at time of first surgery* | 4 (33.3) | 9 (37.5) | >0.99 |
| Azathioprine at time of first surgery | 0 (0) | 2 (8.3) | 0.54 |
| Naïve to biologic drugs | 2 (16.6) | 13 (54.2) | 0.04 |
| Drugs other than anti-UC drugs | 1 (8.3) | 7 (29.2) | 0.2 |
| EIMs | 7 (58.3) | 4 (16.7) | 0.02 |
| Three-stage procedure | 5 (41.7) | 4 (16.7) | 0.12 |
| Hand-sewn anastomosis | 4 (33.3) | 9 (37.5) | >0.99 |
| Major perioperative complications | 1 (8.3) | 1 (4.2) | >0.99 |
| Pouchitis | |||
| At least one episode | 3 (25) | 3 (12.5) | 0.38 |
| Relapsing at least once | 3/3 (100) | 1/3 (33.3) | 0.09 |
IPAA: ileal-pouch anal anastomosis; BMI: body mass index; UC: ulcerative colitis; EIMs: extraintestinal manifestations.
*>20 mg of corticosteroids.