Table 7.
TCM prescriptions with potential FASN inhibitory effect. Among these six commonly used antitumor prescriptions, all of them contain herbs with FASN inhibitory effect. Although studies have shown the antitumor effect of these prescriptions, a lack of studies have been carried out investigating their pharmacological actions and the underlying mechanisms.
| Number | Name of the Prescription | Composition | Effect |
|---|---|---|---|
| 1 | Chaihu Shugan Powder (柴胡疏肝散) |
Pericarpium Citri reticulatae (陳皮); Root of Chinese thorowax (柴胡); Rhizoma Ligustici (川芎); Fructus Aurantii (枳殼); The root of Paeonia lactiflora Pall. (芍藥); Radix glycyrrhizae Preparata (炙甘草); Rhizoma cyperi (香附) |
1. Smoothing Liver and Regulating Qi 2. Invigorating Blood Circulation and Alleviate Pain |
|
| |||
| 2 | Taoren Chengqi Decoction (桃核承氣湯) |
Semen persicae (桃仁); Radix glycyrrhiza (甘草); Mirabilite (芒硝); Rhuen palmatum L. (大黃); Ramulus Cinnamomi (桂枝) | Promoting Blood Circulation for Removing Blood Stasis |
|
| |||
| 3 | Fuyuan Huoxue Decoction (復元活血湯) |
Root of Chinese Thorowax (柴胡); Radix Trichosanthis (瓜蔞根); Chinese angelica (當歸); Flos carthami (紅花); Radix Glycyrrhizae (甘草); Squama manis (穿山甲); Rhuen palmatum L. (大黄); Semen Persicae (桃仁) | Promoting Blood Circulation for Removing Blood Stasis |
|
| |||
| 4 | Xuefu Zhuyu Decoction (血府逐瘀湯) |
Chinese angelica (當歸); Rehmannia glutinosa Libosch (生地); Semen persicae (桃仁); Flos carthami (紅花); Fructus Aurantii (枳殼); Paeonia vaitchii Lynch (赤芍); Root of Chinese thorowax (柴胡); Radix glycyrrhizae (甘草); Platycodon grandiforus (桔梗); Rhizoma ligustici Chuanxiong (川芎); Radix Achyranthis bidentatae (牛膝) | 1. Promoting Blood Circulation for Removing Blood Stasis 2. Promoting the Qi Circulation and Stopping Pain |
|
| |||
| 5 | Wenjing Decoction (溫經湯) |
Tetradium ruticarpum (吳茱萸); Chinese angelica (當歸); Rhizoma Ligustici Chuanxiong (川芎) The root of Paeonia lactiflora Pall. (芍藥); Panax ginseng C. A. Mey. (人參); Ramulus Cinnamomi (桂枝); Colla Corii Asini (阿膠) Paeonia suffruticosa Andr. (牡丹皮); Zingiber officinale (生薑); Radix glycyrrhizae (甘草); Pinellia ternata (半夏); Radix ophiopogonis (麥門冬) | 1. Promoting Blood Circulation for Removing Blood Stasis 2. Warming Channel for Dispelling Cold |
|
| |||
| 6 | Xiaoyao Powder (逍遙散) |
Root of Chinese thorowax (柴胡); Chinese angelica (當歸); The root of Paeonia lactiflora Pall. (白芍); Atractylodes macrocephala (白術); Wolfiporia cocos (茯苓); Rhizoma Zingiberis Recens (生薑); Mentha haplocalyx (薄荷); Radix glycyrrhizae Preparat (炙甘草) | 1. Smoothing Liver and Regulating Qi 2. Promoting Blood Circulation for Removing Blood Stasis |
In Composition, Herbal Medicines with the screening of FASN inhibitory effect are bolded.