Table 2.
Adjusted Associationsa of Clinical Trial Enrollment With Terminal Illness Acknowledgment, EOL Care Preferences, and Advance Care Planning; N = 358
| Total | Enrollment in Trial | Unadjusted Analyses | Adjusted Analyses | ||||
|---|---|---|---|---|---|---|---|
| n/N (%) | Yes; n=37 | No; n=321 | OR (95% CI) | P-value | OR (95% CI) | P-value | |
| Terminal illness acknowledgment | 125/322 (38.8) | 9 (27.3) | 116 (40.1) | 0.56 (0.25,1.25) | 0.155 | 0.72 (0.30, 1.71) | 0.458 |
| Desires prognostic information | 236/326 (72.4) | 16 (50.0) | 220 (74.8) | 0.34 (0.16, 0.71) | 0.004 | 0.37 (0.18, 0.79) | 0.01 |
| Values life-extension over comfort | 83/290 (28.6) | 14 (48.3) | 69 (26.4) | 2.60 (1.19, 5.66) | 0.016 | 2.02 (0.86, 4.75) | 0.108 |
| EOL discussion | 151/357 (42.3) | 6 (16.2) | 145 (45.3) | 0.23 (0.09, 0.58) | 0.002 | 0.30 (0.11, 0.78) | 0.014 |
| DNR order | 138/323 (42.7) | 8 (25.0) | 130 (44.7) | 0.41 (0.18, 0.95) | 0.037 | 0.51 (0.20, 1.26) | 0.142 |
| Living will or health care proxy | 181/321 (56.4) | 18 (54.5) | 163 (56.6) | 0.92 (0.45, 1.90) | 0.821 | 0.77 (0.35, 1.73) | 0.532 |
a
Analyses were adjusted for sociodemographic and clinical confounders. Covariates of age, gender, income, marital status, insurance, education, race/ethnicity, religion, recruitment site, cancer type, performance status, Charlson Comorbidity Index, McGill QOL and subscales, coping, and religious coping were entered into models when related to clinical trial enrollment and the outcome of interest with P<0.10, and were retained in the model when remaining significant with P<0.05.