Figure 5.

Competition binding curve of 2-phenyl-5-oxo- 7-methyl-1,3,4-oxadiazolo[a,2,3]-pyrimidine as a new benzodiazepine agonist. IC50 curve shows the effect of competitor concentration on the inhibition of radioligand binding. The IC50 value is the concentration of competitor that correlates to the midpoint between the high and low plateaus of the curve.

Each point represents Mean ± SEM of three independent determinations.