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Progressive mitochondrial swelling in the brain mitochondria isolated from ketamine (30 mg/Kg ip × 5 days) treated rats compared with those of control rats. Mitochondrial swelling was measured through the determination of absorbance at 530 nm as described in Materials and methods. Values represented as mean ± SD (n = 3). * represents P < 0.05 and *** represents P < 0.001 significant difference compared to control mitochondria
