Table 3.
Comparison of clinical and laboratory parameters according to EHRI tertiles.
| Clinical parameters | EHRI tertiles | P | ||
|---|---|---|---|---|
| T1 (N = 28) | T2 (N = 27) | T3 (N = 27) | ||
| Age (years)1 | 0.345 | |||
| Mean ± SD | 57.7 ± 12.7 | 56.7 ± 17.5 | 62.1 ± 12.9 | |
| Sex | ||||
| Men | 19 (67.8) | 14 (51.8) | 10 (37.0) | 0.073 |
| Women | 9 (32.2) | 13 (48.2) | 17 (63.0) | |
| BMI (kg/m2) | ||||
| Mean ± SD | 23.7 ± 3.3 | 24.5 ± 3.5 | 22.1 ± 2.7 | 0.027* |
| Chronic kidney disease | ||||
| Diabetes | 14 (50.0) | 12 (44.4) | 18 (66.7) | 0.233 |
| Nondiabetes | 14 (50.0) | 15 (55.6) | 9 (33.3) | |
| Kt/V | 1.38 ± 0.21 | 1.38 ± 0.30 | 1.48 ± 0.21 | 0.239 |
| Hemoglobin (g/dL) | 10.1 ± 0.8 | 9.9 ± 0.6 | 9.5 ± 0.5 | 0.001 |
| WBC count (/mm3) | 7,241 ± 1,965 | 6,710 ± 1,412 | 6,643 ± 1,844 | 0.423 |
| Iron (ug/dL) | 71.2 ± 27.2 | 72.6 ± 22.7 | 62.5 ± 32.4 | 0.352 |
| Ferritin (ng/mL)1 | 359.1 ± 273.0 | 356.8 ± 388.4 | 301.7 ± 261.2 | 0.745 |
| TSAT (%)1 | 33.4 ± 11.6 | 34.7 ± 11.2 | 32.0 ± 13.5 | 0.703 |
| Albumin (g/dL) | 3.6 ± 0.5 | 3.5 ± 0.5 | 3.3 ± 0.5 | 0.089 |
| CRP (mg/dL)1 | 0.63 ± 1.16 | 0.69 ± 0.84 | 1.22 ± 2.20 | 0.303 |
| T. cholesterol (mg/dL)1 | 165.9 ± 28.6 | 167.0 ± 44.0 | 152.3 ± 59.6 | 0.420 |
| Calcium (mg/dL)1 | 8.1 ± 0.8 | 8.1 ± 0.7 | 8.1 ± 0.6 | 0.992 |
| Phosphate (mg/dL) | 4.9 ± 0.9 | 5.0 ± 0.9 | 4.4 ± 1.1 | 0.053 |
| nPCR (g/kg/d) | 0.785 ± 0.297 | 0.819 ± 0.286 | 0.713 ± 0.269 | 0.394 |
| iPTH (pg/mL)1 | 249.2 ± 145.6 | 190.2 ± 161.8 | 170.6 ± 147.4 | 0.148 |
*The difference was shown between T2 and T3.
1These parameters were compared using Kruskal-Wallis test and the other parameters were compared using ANOVA.
EHRI: ESA hyporesponsiveness index; BMI: body mass index; WBC: white blood cell; TSAT: transferrin saturation; CRP: C-reactive protein; T. cholesterol: total cholesterol; nPCR: normalized protein catabolic rate; iPTH: intact parathyroid hormone.