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Adverse event rates between the two groups
| Adverse effects | BID group | PRN group | P. value |
|---|---|---|---|
| Gastrointestinal upset (%) | 8 (13.3%) | 4 (6.7%) | - |
| No adverse events (%) | 54 (87.7%) | 56 (93.3%) | <0.001 |
| Gastrointestinal bleeding (%) | 0 | 0 | - |
BID: twice daily; PRN: as needed
