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(A) Human serum MG (sMG) levels predict changes in cognition over time. Levels of fasting sMG at baseline are plotted against changes (Δ) in MMSE of healthy older adults, over 9 mo. (B) Changes (Δ) in sMG levels over time correlate with changes (Δ) in HOMA-IR over the same period. All tests were performed in fasting sera; fitted regression lines are as shown.
