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. 2014 Mar 25;5(2):e00956-14. doi: 10.1128/mBio.00956-14

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Copyright © 2014 Ran et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-ShareAlike 3.0 Unported license, which permits unrestricted noncommercial use, distribution, and reproduction in any medium, provided the original author and source are credited.

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FIG 9 — Correlation of the F_opt values and dN/dS ratios (R values) of different functional classes of genes of prokaryotes. The data for all 120 ATGC were pooled. (a) Comparison of R values of two broad categories of genes, those encoding proteins involved in information processing and cellular functions (e.g., cell division) (cell&infor) and those encoding proteins involved in metabolism (enzymes and transporters). The mean R value of the metabolic class (red box) is −0.242, which is significantly greater than the mean R value of −0.223 of the informational class (P < 0.02). (b) Comparison of R values of individual functional categories of genes. The functional categories are from the COG classifications.