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. 2014 Apr 1;5(2):e01017-14. doi: 10.1128/mBio.01017-14

TABLE 2 .

Constitutive expression of bbd18 prevents B. burgdorferi infection of mice by tick transmission

Straina No. of infected mice/no. of mice fed on by infected larvaeb No. of infected mice/no. of mice fed on by infected nymphsb
WT 2/2 5/5
WT+cBBD18 0/6c 0/7c
a

Mice were fed upon by ticks infected with B. burgdorferi strains S9 (WT) or S9/pBSV2*flaBp-bbd18 (WT+cBBD18).

b

Mouse infection determined by seroconversion to B. burgdorferi whole-cell lysates and isolation of spirochetes from mouse tissues 3 weeks after tick feeding.

c

P value of <0.05 compared to WT using Fisher’s exact test.