. 2014 Apr 1;5(2):e01017-14. doi: 10.1128/mBio.01017-14

TABLE 3 .

Constitutive production of an inactive BBD18 variant does not prevent B. burgdorferi infection in mice

Strain^a	No. of seropositive mice/no. of mice injected^b	No. of tissue isolates/no. of mice injected (ear, bladder, joint)^c
WT	4/4	4/4, 4/4, 4/4
WT+cBBD18v3	4/5	4/5, 4/5, 4/5
WT+cBBD18v4	0/5	0/5, 0/5, 0/5^d

^{^a}

Mice were inoculated with B. burgdorferi strains S9 (WT), S9/pBSV2*flaBp-bbd18v3 (WT+cBBD18v3), or S9/pBSV2*flaBp-bbd18v4 (WT+cBBD18v4).

^{^b}

Seroconversion to B. burgdorferi whole-cell lysates was assessed by immunoblotting 3 weeks after needle inoculation of 10⁴ spirochetes.

^{^c}

Isolation of spirochetes from mouse tissues was attempted 32 days after inoculation.

^{^d}

P value of <0.005 compared to WT and P value of <0.05 compared to WT+cBBD18v3, using Fisher’s exact test.