TABLE 1 .

Genes coregulated with asi-1 (NCU05257) across wild strains are affected by asi-1 deletion^a

ID	Annotation	DE P value	Coexpression correlation
NCU00522	Cystathionine beta-lyase	2.3104e−05	0.78
NCU00535	Alanyl-tRNA synthetase	0.0054	0.84
NCU02019	FAD-dependent oxidoreductase	1.5469e-08	0.82
NCU02543	Aspartate aminotransferase	0.0027	0.92
NCU05045	MFS monocarboxylate transporter	1.8375e−09	0.90
NCU05256	Hypothetical	0.0013	0.81
NCU07126	Acetyltransferase (GNAT) family	0.0503	0.83
NCU11365	Aminotransferase	0.0533	0.82

^aEach row shows analysis of one gene whose expression changed significantly upon deletion of asi-1 and was tightly correlated with expression of asi-1 across Louisiana strains of N. crassa. DE P value, Benjamini-Hochberg-corrected significance of differential expression between an engineered asi-1 deletion mutant and an isogenic wild-type-strain; the complete set of genes responsive to asi-1 deletion is given in Data Set S2 in the supplemental material. Coexpression correlation, Spearman’s rank correlation coefficient between the expression levels of the indicated gene and asi-1 across Louisiana isolates; the complete set of genes coregulated with asi-1 is given in Table S2. ID, identifier.