TABLE 3 .

DMV and intracellular virion (IV) prevalence in infected cells

Conditions	Virus	ts	No. of cells	Prevalence of intracellular signs of infection				No. per cell section when present				Rel. DMV capacity (%)b
				DMV (%)	Pa	IV (%)	P	DMV	P	IV	P
DBT, 33°C, 5.5 hpi	Wild type		323	6		7	−	18 ± 20		3 ± 4	−	100 ± 60
	Brts31	nsp3	753	2	8 × 10−4	7	NSc	6 ± 6	1 × 10−2	3 ± 4	NS	20 ± 12
17Cl-1, 33°C, 10 hpi	Wild type		161	40		29		9 ± 9		4 ± 3		100 ± 48
	Brts31	nsp3	238	24	4 × 10−4	25	NS	7 ± 8	4 × 10−4	4 ± 6	NS	35 ± 18
	Albts16	nsp5	120	37	NS	19	NS	9 ± 8	NS	4 ± 4	NS	53 ± 28
	Brts105	nsp14	230	22	1 × 10−4	32	NS	9 ± 13	NS	4 ± 4	NS	49 ± 25
	Wüts18	nsp16	140	36	NS	20	NS	9 ± 10	NS	2 ± 1	7 × 10−3	71 ± 36
	Albts22d	nsp12	320	13	1 × 10−5	9	1 × 10−5	6 ± 5	NS	1 ± 0.4	1 × 10−5	16 ± 10

^aCalculated by Fisher’s exact test.

^bRelative DMV capacity was calculated as follows: average DMV size (± standard deviation) × percentage of cell sections with DMVs × DMVs per section, relative to wild-type.

^cNot significantly different from the corresponding wild-type control.

^dAttenuated growth at 33°C compared to the wild type.