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. 2014 Mar 20;2014:658479. doi: 10.1155/2014/658479

Figure 2.

Figure 2

(a) Vascular responses to acetylcholine (ACh) and (b) sodium nitroprusside (SNP) in isolated femoral arteries of 7- and 22-week-old Wistar-Kyoto (WKY) and spontaneously hypertensive rats (SHR). Values represent mean ± SEM of 6–8 rats. SHR-7: 7-week-old SHR; SHR-22: 22-week-old SHR; WKY-7: 7-week-old WKY rats; WKY-22: 22-week-old WKY rats. Symbols have the following meanings: x P < 0.05 compared to age-matched WKY (SHR-7 versus WKY-7, SHR-22 versus WKY-22), § P < 0.05, compared to maximal relaxation at ACh concentrations 0.3 μmol/L—this significance indicates the release of counterbalancing contracting factors in hypertensive animals.