(b) Multivariable Cox regression model in HER2-negative patients since 2006
| Characteristic | Overall survival (n = 2727, events = 219) | ||
|---|---|---|---|
| HR | 95% CI | P value | |
| CHT + AHT (n = 671, events = 23) |
Reference | — | — |
| AHT (n = 1392, events = 104) |
2.33 | 1.40; 3.87 | 0.001 |
| CHT (n = 279, events = 28) |
3.15 | 1.61; 6.16 | 0.001 |
| No adjuvant therapy (n = 385, events = 64) |
4.91 | 2.81; 8.59 | <0.001 |
Model is controlled for age, Ki67 categories, tumor size, nodal status, grading, and receptor status; HR: hazard ratio; 95% CI: 95% confidence interval.