Table 2.
Cockcroft and Gault [69] | eCCr = (140−age) × weight in kg/(72 × Scr), ×0.85 in females |
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Six-variable MDRD [71] | 170 ∗ [Scr]−0.999 ∗ [age]−0.176 ∗ [BUN]−0.170 ∗ [serum albumin]0.318, ∗0.762 in females, ∗1.180 if black |
| |
Four-variable MDRD [71] | [186.3 × (Scr)−1.154 × (age)−0.203], ×0.742 in females, ×1.212 if black |
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CKD-EPI (creatinine) [77] | Female (Scr ≤ 0.7), eGFR = 144 × (Scr/0.7)−0.329 × (0.993)Age
(Scr > 0.7), eGFR = 144 × (Scr/0.7)−1.209 × (0.993)Age Male (Scr ≤ 0.9), eGFR = 141 × (Scr/0.9)−0.411 × (0.993)Age (Scr > 0.9), eGFR = 141 × (Scr/0.9)−1.209 × (0.993)Age |
| |
CKD-EPI (cystatin C) [80] | (Scys ≤ 0.8), eGFR = 133 × (Scys/0.8)−0.499 × 0.996Age [×0.932 if female] (Scys > 0.8), eGFR = 133 × (Scys/0.8)−1.328 × 0.996Age [×0.932 if female] |
| |
CKD-EPI (cystatin C-creatinine) [80] | Female (Scr ≤ 0.7) (Scys ≤ 0.8), eGFR = 130 × (Scr/0.7)−0.248 × (Scys/0.8)−0.375 × 0.995Age [×1.08 if black] (Scr ≤ 0.7) (Scys > 0.8), eGFR = 130 × (Scr/0.7)−0.248 × (Scys/0.8)−0.711 × 0.995Age [×1.08 if black] |
Female (Scr > 0.7) (Scys ≤ 0.8), eGFR = 130 × (Scr/0.7)−0.601 × (Scys/0.8)−0.375 × 0.995Age [×1.08 if black] (Scr > 0.7) (Scys > 0.8), eGFR = 130 × (Scr/0.7)−0.601 × (Scys/0.8)−0.711 × 0.995Age [×1.08 if black] | |
Male (Scr ≤ 0.9) (Scys ≤ 0.8), eGFR = 135 × (Scr/0.9)−0.207 × (Scys/0.8)−0.375 × 0.995Age [×1.08 if black] (Scr ≤ 0.9) (Scys > 0.8), eGFR = 135 × (Scr/0.9)−0.207 × (Scys/0.8)−0.711 × 0.995Age [×1.08 if black] | |
Male (Scr > 0.9) (Scys ≤ 0.8), eGFR = 135 × (Scr/0.9)−0.601 × (Scys/0.8)−0.375 × 0.995Age [×1.08 if black] (Scr > 0.9) (Scys > 0.8), eGFR = 135 × (Scr/0.9)−0.601 × (Scys/0.8)−0.711 × 0.995Age [×1.08 if black] | |
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BIS1 [81] | 3736 × creatinine−0.87 × age−0.95 × 0.82 (if female) |
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BIS2 [81] | 767 × cystatin C−0.61 × creatinine−0.40 × age−0.57 × 0.87 (if female) |
eCCr: estimated creatinine clearance; Scr: serum creatinine; BUN: blood urea nitrogen; Scys: serum cystatin C; MDRD: Modification of Diet in Renal Disease; CKD-EPI: Chronic Kidney Disease Epidemiological Collaboration; BIS: Berlin Initiative Study.