Table 1.

Treatment of anti-phospholipid antibodies in pregnancy.

Clinical presentation	Suggested treatment
Patients with aPL and no history of thrombosis and no series of fetal loss or early delivery due to preeclampsia or placental insufficiency	Addition of low-dose aspirin throughout pregnancy
Patients with APS and no history of thrombosis but with previous history of stillbirth, recurrent fetal loss, or other APS-associated pregnancy complications	Heparin or LMWH (usual prophylactic dose) during pregnancy and 6 weeks postpartum Low-dose aspirin throughout pregnancy
Patients with APS and prior history of thrombosis or embolism	Heparin or LMWH (usual therapeutic dose) during pregnancy and 6 weeks postpartum followed by optional conversion on warfarin Low-dose aspirin throughout pregnancy