Table 8.
Groups/(g/kg·bw) | Fetal rats number | Hypoplasia incidence/(%) | ||||
---|---|---|---|---|---|---|
Spine/P | Sternum/P | Pelvis/P | Metacarpal/P | Phalanx/P | ||
Negative controls | 71 | 0.0/— | 11.3/— | 1.4/— | 11.3/— | 18.3/— |
5.0 | 71 | 1.4/1.000 | 9.8/0.785 | 1.4/1.000 | 12.7/0.796 | 14.1/0.494 |
10.0 | 72 | 0.0/— | 13.9/0.637 | 2.8/1.000 | 9.7/0.763 | 12.5/0.336 |
20.0 | 69 | 0.0/— | 13.0/0.748 | 1.4/1.000 | 17.4/0.301 | 15.9/0.710 |
Positive controls | 50 | 18.0/0.001 | 40.0/0.000 | 24.0/0.000 | 32.0/0.005 | 38.0/0.016 |