Table 2.

Summary of factors secreted by neuroprogenitors and the potential effect they have on microglia in vitro.

NPC secreted factors	Reference	Modulation of microglia	Reference
BDNF	[18]	Proliferation and induction of phagocytic activity	[35]
Haptoglobin	[24]	Neuroprotection	[36]
IL-1β	[37]	Intracellular Ca+2 elevation and proliferation	[22]
IL-6	[37]	Increase in proliferation	[38]
M-CSF	[20]	Mitogen	[39]
NGF	[40]	Decrease in LPS-induced NO	[41]
TGFβ	[37]	Inhibition of TNFα secretion	[42]
TNFα	[37]	Upregulation of IL-10 secretion	[43]
VEGF	[20]	Induction of chemotaxis and proliferation	[20]