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. 2014 Apr 2;14:e15.

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Copyright © 2014 The Author(s)

This is an open-access article whereby the authors retain copyright of the work. The article is distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Pressure distribution, studied in vivo. Wounds were treated with different device, dressing and filler combinations set to provide NPWT at −80 mm Hg. The horizontal line (—) indicates the −80 mm Hg set point of the NPWT pumps. The arrow indicates the combination that represents the PICO™ system with no filler. The pressure was measured in the wound bed of defect wounds (top panel) or on top of the suture line of incisional wounds (bottom panel). Results are shown as means ± SEM of 8 experiments.