Table 1.
Baseline patient characteristics
| Characteristic | |
|---|---|
| Age, y | |
| Mean (SD) | 69.9 (6.8) |
| Range | 62-86 |
| Male, n (%) | 16 (100.0) |
| White, non-Hispanic ethnicity, n (%) | 15 (93.8) |
| Hand with 1 or more contractures, n (%) | |
| Left | 5 (31.3) |
| Right | 4 (25.0) |
| Both | 7 (43.8) |
| Affected joints per affected hand, n | |
| Mean (SD) | 2.0 (1.0) |
| Range | 1-4 |
| Affected MCP joints per patient, n | |
| Mean (SD) | 1.2 (0.7) |
| Range | 0-3 |
| Affected PIP joints per patient, n | |
| Mean (SD) | 0.5 (0.5) |
| Range | 0-2 |
| Family history of Dupuytren contracture, n (%) | 2 (12.5) |
| History of risk factors and associated conditions, n (%) | |
| Diabetes | 6 (37.5) |
| Current tobacco use | 6 (37.5) |
| Previous tobacco use | 6 (37.5) |
| Current alcohol use | 5 (31.3) |
| Hand trauma | 3 (18.8) |
| Knuckle pads | 2 (12.5) |
| Vibration exposure | 1 (6.3) |
| Epilepsy | 0 (0.0) |
| Ledderhose disease | 0 (0.0) |
| Peyronie disease | 0 (0.0) |
| Age at diagnosis, y | |
| Mean (SD) | 60.8 (11.7) |
| Disease first detected by, n (%) | |
| Finger bending | 12 (75.0) |
| Nodules | 3 (18.8) |
| Pain | 6 (37.5) |
| Duration of symptoms when medical treatment first sought, mo | |
| Mean (SD) | 48.8 (73.9) |
| Median (range) | 24.0 (6-312) |
| Prior treatment for Dupuytren contracture, n (%) | |
| None | 12 (75.0) |
| Surgery | 3 (18.8) |
| Injection | 2 (12.5) |
| Hand therapy | 1 (6.3) |
| Other | 0 (0.0) |
| Patient rating of disease severity at baseline, n (%) | |
| Mild | 4 (25.0) |
| Moderate | 5 (31.3) |
| Severe | 7 (43.8) |
| Physician rating of disease severity, n (%) | |
| Mild | 4 (14.8) |
| Moderate | 7 (25.9) |
| Severe | 16 (59.3) |
| Baseline contracture of treated joints (degrees) | |
| MCP contracture, mean (SD) | 48.3 (24.7) |
| PIP contracture, mean (SD) | 77.8 (25.9) |