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. Author manuscript; available in PMC: 2014 Apr 7.
Published in final edited form as: Neuroscience. 2008 Oct 2;158(2):474–483. doi: 10.1016/j.neuroscience.2008.09.039

Figure 4.

Figure 4

Effect of siRNA targeting mouse MOP-r on heroin-induced conditioned place preference expressed as mean (+SEM) increased time spent in the conditioning chamber are shown in Fig 4. A. A two-tailed t-test showed that pretreatment with siRNA targeting mouse MOP-r (“MUMR1”) prior to heroin blocked the formation of a conditioned place preference. B. Pretreatment with siRNA targeting mouse MOP-r (“MORD2”) attenuated the formation of conditioned place preference induced by heroin. C. Infusion of siRNA (“MORD4”) targeting mouse MOP-r did not affect the formation of conditioned place preference induced by heroin.