TABLE 2.

Patient Outcomes from a Mathematical Model of the Use of Fecal Transplantation to Prevent Clostridium difficile Infection and Recurrence in a Simulated 12-Bed Intensive Care Unit over a 1-Year Period

Scenario, treatment level, %	Median recurrence (25th percentile, 75th percentile)	Pa	Median incidence (25th percentile, 75th percentile)	Pa
Baseline, 0	2 (0, 6)		0 (0, 1)
After infection
20	1 (0, 4)	<.001	0 (0, 1)	.39
40	1 (0, 4)		0 (0, 1)
60	1 (0, 3)		0 (0, 1)
80	0 (0, 1)		0 (0, 2)
100	0 (0, 1)		0 (0, 1)
After receipt of high-risk medication (antibiotics)
Antibiotics
20	1 (0, 5)	.36	0 (0, 1)	.003
40	1 (0, 6)		0 (0, 1)
60	1 (0, 6)		0 (0, 1)
80	2 (0, 6)		0 (0, 1)
100	1 (0, 6)		0 (0, 1)
Antibiotics and PPIs
20	2 (0, 5.25)	.56	0 (0, 1)	.001
40	2 (0, 6)		0 (0, 1)
60	1 (0, 5)		0 (0, 1)
80	2 (0, 5)		0 (0, 1)
100	2 (0, 6)		0 (0, 1)
Combined
20	1 (0, 5)	<.001	0 (0, 1)	.02
40	1 (0, 4)		0 (0, 1)
60	1 (0, 3)		0 (0, 1)
80	0 (0, 2)		0 (0, 1)
100	0 (0, 1)		0 (0, 1)

NOTE. PPI, proton pump inhibitor.

^aKruskal-Wallis 1-way analysis of variance test.