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. Author manuscript; available in PMC: 2015 Feb 1.
Published in final edited form as: Arterioscler Thromb Vasc Biol. 2013 Dec 5;34(2):338–345. doi: 10.1161/ATVBAHA.113.302785

Fig. 1. Lack of aplnra activity causes lymphatic vessel defects.

Fig. 1

(A) Gross morphology (top panels) and vascular structures (bottom panels) in 4dpf aplnra MO-injected embryos. (B) The loss of LECs in thoracic duct (white arrows) in 4dpf aplnra MO-injected embryos. (C) Quantification of the number of LECs in control and aplnra MO-injected embryos. LECs within the thoracic duct between 8th and 15th somites were counted. All embryos shown have Tg(fli1a:nEGFP);Tg(kdrl:mCherry) double transgenic background to visualize BECs (shown as yellow) and LECs (shown as green). DA, dorsal aorta; CV, cardinal vein; ISV, inter-segmental vessel. Scale bars are 400μm (A) and 50μm (B).