Table 2. Antimicrobial susceptibility and MICs of 175 S.pneumoniae strains isolated from respiratory infection Children younger than 5 years.
Antibiotic agents | MIC (μg/ml) | No. of isolates (%) | Non-susceptible rate (%) | ||||
50% | 90% | range | Resistant | Intermediate | Susceptible | ||
Erythromycin | ≥1 | ≥1 | ≥1 | 175(100.0) | 0(0.0) | 0(0.0) | 100.0 |
Penicillin G | 2 | ≥8 | ≤0.031–≥8 | 20(11.4) | 49(28.0) | 106(60.6) | 39.4 |
Cefotaxime | 2 | ≥4 | ≤0.06–>4 | 43(24.6) | 54(30.9) | 78(44.6) | 55.4 |
Ceftriaxone | 1 | ≥4 | ≤0.06–≥4 | 14(22.6) | 10(16.1) | 38(61.3) | 38.7 |
Amoxicillin | ≤2 | ≥8 | ≤0.06–≥8 | 44(25.1) | 30(17.1) | 101(57.7) | 42.3 |
Co-trimoxazole | ≥4 | 16 | ≤0.5–≥32 | 147(84.0) | 19(10.9) | 9(5.1) | 94.9 |
Clindamycin | ≥1 | ≥1 | ≥1 | 175(100.0) | 0(0.0) | 0(0.0) | 100.0 |
Tetracycline | ≥8 | ≥16 | ≤1–≥16 | 163(93.2) | 2(1.1) | 10(5.7) | 94.3 |
Levofloxacin | ≤2 | ≤2 | ≤0.5–≤2 | 0(0.0) | 0(0.0) | 175(100.0) | 0.0 |
Chloromycetin | ≤4 | 4 | ≤2–≥32 | 8(4.6) | 0(0.0) | 167(95.4) | 4.6 |
Vancomycin | ≤1 | ≤1 | ≤1 | 0(0.0) | 0(0.0) | 175(100.0) | 0.0 |