Table 1.
Amino acid sequences of alamethicin, several WALP peptides, and magainin-H2. Underlined amino acids are non-natural: A and F refer to α-aminoisobutyric acid and C-terminal phenylalaninol, respectively56, 57 (Fig. S5 in the supplementary material44). All sequences form transmembrane helices.21, 56, 58 The N- and C-terminus of each peptide are capped by an acetyl and n-methyl amide groups, respectively (except alamethicin, for which the C-terminus is embedded in the last phenylalaninol).
Name | Sequence |
---|---|
Alamethicin | APAAA AQAVA GLAPV AAEQF |
WALP23 | GWWLA LALAL ALALA LALAL WWA |
WALP27 | GWWLA LALAL ALALA LALAL ALALW WA |
Magainin-H2 | IIKKF LHSIW KFGKA FVGEI MNI |