. Author manuscript; available in PMC: 2015 Apr 1.

Published in final edited form as: J Mol Cell Cardiol. 2014 Feb 5;69:43–51. doi: 10.1016/j.yjmcc.2014.01.017

Table 1.

Changes in cardiac electrophysiological intervals in mice subject to M receptor manipulation

Treatment	N	Timing	Heart rate (beats/min)	RR (ms)	PR (ms)	QRS (ms)	QT (ms)
Pilocarpine	5	Before	673.8±15.21	89.04±2.13	29.58±0.26	8.64±0.46	19.63±1.17
Pilocarpine	5	After	552.7±12.84^*^#	108.55±2.96^*^#	31.85±0.55^*^#	9.49±0.53	19.88±1.18
Saline	5	Before	687.6±13.85	87.26±2.02	30.31±0.44	7.43±0.32	19.89±1.19
Saline	5	After	684.5±11.98	87.66±1.92	29.71±0.97	7.53±0.60	19.52±0.92
Methoctramine	5	Before	672.0±14.67	89.28±2.09	29.54±0.65	8.61±0.29	19.40±0.59
Methoctramine	5	After	743.6±17.45^*^#	80.69±1.81^*^#	28.67±0.40^*^#	7.89±0.31	19.08±0.66

ECG tracings were analyzed from mice treated with muscarinic modulators for 24 hours for modifications of electrical movement during muscarinic receptor manipulation. RR, PR, QRS, and QT indicate the R-R interval, the P-R interval, the QRS complex, and the QT interval, respectively.

: p<0.05 vs. respective saline after treatment;

: p<0.05 vs. the same group before treatment.