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. 2014 Apr 7;9(4):e94082. doi: 10.1371/journal.pone.0094082

Figure 8. Transfection of lymphatics with ca-ROCK protein increases tone.

Figure 8

Isolated, fura-2 loaded rat mesenteric lymphatics were treated with ca-ROCK protein (final concentration 2 μg/ml) combined with TransIT-LT1 (8 μl/ml final), or with the same amount of TransIT-LT1 alone (Vehicle). A. Mean EDD/MaxD. B. Mean ESD/MaxD. C. Mean AMP/MaxD. D. Mean tone. E. Mean CF. F. Mean diastolic 340/380 ratio. G. Mean change in the 340/380 ratio during Ca2+ transients. *P<0.05 versus baseline (BL), same treatment group. N = 5 vessels for the ca-ROCK group, and N = 6 vessels for the vehicle group.