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. Author manuscript; available in PMC: 2014 Apr 7.
Published in final edited form as: Nature. 2009 Feb 8;458(7236):346–350. doi: 10.1038/nature07712

Figure 1.

Figure 1

Model for systemic RNAi viral immunity in Drosophila melanogaster. Upon viral infection, virus-specific dsRNAs (eg., replication intermediates) are generated during the initial rounds of virus replication. Following cell death or lysis, dsRNAs are taken up and processed by uninfected cells to protect them from subsequent infection, thereby preventing virus spread.