Table 4.

Clinical presentation of colon cancer recurrence

Case no	Gender	Presenting problem	Routine vs. interval	Diagnostic tests	Metastatic site	Time to diagnosis (days)	Metastasis surgery	Time to surgery (days)
GP-surveillance
1	F	Elevated CEA	Routine	CEUS	Disseminated	27	No	Inoperable
				PET CT
2	M	Abdominal pain	Interval	CEUS	Liver	21	No	Inoperable
3	M	Elevated CEA	Routine	CEA	Disseminated	71	No	Inoperable
				CT thorax
				CT abdomen
4	M	Metastatic lesion detected at CEUS	Routine	CEUS	Liver	4	Yes	38
				CT thorax
				CT abdomen
5	F	Abdominal pain, normal CEA, CT and CEUS, disseminated cancer detected at laparotomy	Interval	CEUS	Disseminated	270	Yes	270
				CT thorax
				CT abdomen
6	M	Abdominal tenderness	Interval	Anorectoscopy	Local recurrence	2	Yes	30
				CT thorax
				CT abdomen
Surgeon-Surveillance
7	M	Metastatic lesion detected chest x-ray	Routine	CT thorax	Lung	45	Yes	62
				CT abdomen
8	M	Stoma bleeding	Interval	Colonoscopy	Local and lymph node recurrence	10	No	Inoperable
				CT thorax
				CT abdomen
9	M	Weight loss	Routine	CT Thorax	Lung	45	No	Inoperable
		Night sweating		CT abdomen
10	M	Metastatic lesion detected at chest-x ray	Routine	CT Thorax	Lung	4	Yes	42
				CT abdomen
11	M	Metastatic lesion detected on CEUS	Routine	MR liver	Liver	3	Yes	43
				CT thorax
				CT abdomen
12	F	Abdominal pain	Interval	CT abdomen	Disseminated	16	No	Inoperable
				CT thorax
13	M	Elevated CEA	Routine	CT thorax	Liver	30	No	Inoperable
				CT abdomen	Lung
				CT liver
14	F	Occult blood in faeces	Interval	CT thorax	Liver	31	Yes	35
				CT abdomen
				CEUS