Table 2.
Serum adenosine deaminase and interferon-γ levels in patients with tuberculosis, malignancy and non-tuberculosis non-malignancy in the study group
| Group 1 (Tuberculosis) (n = 23) | Group 2 (Malignancy) (n = 11) | Group 3 (Non-tuberculosis non-malignancy) (n = 18) | p Value | ||
|---|---|---|---|---|---|
| Age (yrs) |
25 (20–37) |
65 (50–68) |
67.5 (45–75) |
0.0001 |
P (1–2) = 0.0001 |
| P (1–3) = 0.0001 | |||||
| P (2–3) = 0.946 | |||||
| Male/female |
15/8 |
7/4 |
15/3 |
0.368 |
|
| Serum ADA-1 (U/L) |
11.32 (4.43-18.01) |
11.52 (8.64-16.24) |
10.81 (6.70-14.89) |
0.983 |
|
| Serum ADA-2 (U/L) |
16.54 (12.11-20.77) |
11.36 (7.16-20.00) |
10.00 (6.59-13.00) |
0.004 |
P (1–2) = 0.068 |
| P (1–3) = 0.001 | |||||
| P (2–3) = 0.393 | |||||
| Serum total ADA (U/L) |
28.98 (24.51-33.66) |
27.39 (15.68-35.14) |
21.70 (17.73-27.05) |
0.034 |
P (1–2) = 0.473 |
| P (1–3) = 0.004 | |||||
| P (2–3) = 0.605 | |||||
| Serum μg/ml (pg/ml) | 75.00 (35.00-160.00) | 50.00 (15.00-90.00) | 57.50 (30.00-115.00) | 0.513 | |
ADA, Adenosine deaminase; IFN-γ, Interferon gamma.
Data are expressed as median (interquartile range).