Table 1.

Clinical Characteristics of Pregnancies for Placentas Studied

a. Maternal Characteristics
	Lean	Obese	P value
n	12	12	---
Gravidity	UK	UK	---
Parity (median, 25–75%)	2, 0.5–3	2.5, 2–5	0.1
Gestational age (weeks)	39 ± 1.1	39.0 ± 1.0	0.9
Maternal age (years)	27.4 ± 6.6	31.7 ± 5.8	0.6
Maternal Weight (lbs.)	130.2 ± 4.0	208.2 ± 6.1*	<0.001
Maternal Height (in)	65.1 ± 0.7	65.2 ± 0.9	0.9
Maternal BMI (kg/m2)	22.1 ± 0.4	35.9 ± 0.9*	<0.001
Race	UK	UK	---
Ethnicity	UK	UK	---
Prenatal Vitamin	Y = 8, N = 1, UK = 2	Y = 8, N = 1, UK = 2	---
Drugs (cigarettes/alcohol)	N/A	N/A	---
Previous prenatal admission(s)	UK	UK	---
Blood pressures <140/90 mm Hg	Y =10, N = 2	Y = 12, N = 0	---
Screened for diabetes	Y = 12	Y = 12	---
Antibiotics in labor	UK	UK	---
Beta strep status	UK	UK	---
Antenatal steroids	UK	UK	---
Magnesium sulfate	UK	UK	---
Anesthesia	UK	UK	---
Cervical ripening agent	UK	UK	---
Induction	Y = 2, N = 8, UK = 2	Y = 1, N = 10, UK = 1	---
C-section	Y = 6, N = 3, UK = 3	Y = 7, N = 4, UK = 1	---
b. Offspring and Umbilical Cord Measures
Birth weight (g)	3256.8 ± 100.3	3312.7 ± 128.6	0.7
Placental weight (g)	647.9 ± 46.4	645.9 ± 36.1	0.9
Offspring Sex	F = 4, M = 8	F = 3, M = 9	---
TG (mg/dl)	10 ± 3.1	8.7 ± 1.9	0.7
NEFA (mmol/l)	0.2 ± 0.03	0.2 ± 0.02	0.6
Cholesterol (mg/dl)	78 ± 8.7	55.4 ± 5.5*	0.03
Glucose (mg/dl)	57 ± 1.6	67 ± 2.8*	0.01
Insulin (pg/ml)	148 ± 32	153 ± 27	0.9
Leptin (pg/ml)	4031 ± 822	7744 ± 1083*	0.03
IL-6 (pg/ml)	1.6 ± 0.6	2.4 ± 0.8	0.4
TNFa (pg/ml)	14.7 ± 1.3	17 ± 1.2	0.2

Values are expressed as mean ± SE unless otherwise stated. Y = yes, N = no, UK = unknown, F = female, M = male, TG = triglyceride, and NEFA = non-esterified fatty acid