Table 2. Scores on the BBB scale in the efficacy study.
Experimental Groups | Mean BBB Score ± SEM on Day 13 | Comparison p Values | |||
---|---|---|---|---|---|
| |||||
Controls | ReGel | 1.5 mg/ml | 3.0 mg/ml | ||
treatment on Day 0* | |||||
9L tumor Day 0 (control) | 5.38 ± 3.54 | NA | 0.621 | 0.007 | 0.004 |
9L tumor & ReGel (vehicle only) Day 0 | 7 ± 2.46 | 0.621 | NA | 0.003 | 0.005 |
9L tumor & 1.5 mg/ml OncoGel Day 0 | 15.25 ± 1.19 | 0.007 | 0.003 | NA | 0.554 |
9L tumor & 3.0 mg/ml OncoGel Day 0 | 14.5 ± 0.33 | 0.004 | 0.005 | 0.554 | NA |
treatment on Day 5† | |||||
9L tumor Day 0 (control) | 3.2 ± 1.08 | NA | 0.162 | 0.013 | 0.016 |
9L tumor Day 0 & ReGel (vehicle only) Day 5 | 5.87 ± 1.35 | 0.162 | NA | 0.108 | 0.29 |
9L tumor Day 0 & 1.5 mg/ml OncoGel Day 5 | 9.25 ± 1.42 | 0.013 | 0.108 | NA | 0.266 |
9L tumor Day 0 & 3.0 mg/ml OncoGel Day 5 | 7.5 ± 0.5 | 0.016 | 0.29 | 0.266 | NA |
Eight rats in each group (32 total).
Five rats in the control group, 8 rats in each of the other 3 groups (29 total).