Table 1. Time trends of in-hospital mortality and disease severity on admission to intensive care unit.
| 1989–1996 | 1997–2004 | 2005–2008 | 2009–2012 | P | |
|---|---|---|---|---|---|
| In-hospital mortality (%) | 112 (71.8) | 96 (60.8) | 67 (41.9) | 57 (35.4) | <0.0005a |
| Child-Pugh class (%) | |||||
| A | 1 (0.7) | 3 (2.1) | 0 (0) | 1 (1.1) | 0.448a |
| B | 28 (19.4) | 29 (20) | 23 (20) | 11 (12.2) | |
| C | 115 (79.9) | 113 (77.9) | 92 (80) | 78 (86.7) | |
| Child-Pugh score | 11.5 (6–15) | 11 (5–15) | 11 (7–15) | 12 (6–15) | 0.203b |
| MELD | 25.8 (9–40) | 24.2 (6–40) | 22.5 (8–40) | 17.9 (7–40) | <0.0005b |
| MELD-sodium | 28 (11–82) | 23.6 (1–40) | 21.7 (5–40) | 17.8 (3–74) | <0.0005b |
| SOFA | 12 (2–21) | 10 (0–19) | 8 (1–31) | 8 (0–17) | <0.0005b |
| APACHE II | 18 (2–41) | 19 (0–44) | 15 (6–42) | 14 (5–25) | <0.0005b |
APACHE, Acute Physiology and Chronic Health Evaluation; MELD, Model for End-Stage Liver Disease; SOFA, Sequential Organ Failure Assessment.
a
χ2-test.
b
The Kruskal–Wallis test.