Table 2.
Comparison between the two quantification methods for both groups. AV-45 mean global and target-to-cerebellum SUVr values and associated standard deviations are shown for the two groups using PET template-based quantification (route 1) and MRI-based quantification (route 2). Significant p values (<.05) are shown
| Region | Patients | CN subjects | ||||
|---|---|---|---|---|---|---|
| Route 1 | Route 2 | p value | Route 1 | Route 2 | p value | |
| Global | 1.47 ± .24 | 1.50 ± .32 | – | 1.25 ± .13 | 1.18 ± .09 | .010 |
| Frontal lobes | 1.49 ± .28 | 1.54 ± .38 | – | 1.29 ± .17 | 1.19 ± .13 | .010 |
| Temporal lobes | 1.42 ± .22 | 1.45 ± .30 | – | 1.19 ± .13 | 1.16 ± .07 | – |
| Insular lobes | 1.37 ± .27 | 1.46 ± .32 | .045 | 1.14 ± .13 | 1.19 ± .11 | – |
| Parietal lobes | 1.54 ± .25 | 1.51 ± .35 | – | 1.26 ± .14 | 1.15 ± .09 | .002 |
| Occipital lobes | 1.43 ± .22 | 1.49 ± .31 | – | 1.24 ± .13 | 1.22 ± .08 | – |
| Orbitofrontal | 1.47 ± .31 | 1.60 ± .41 | .011 | 1.22 ± .17 | 1.23 ± .16 | – |
| Anterior cingulate | 1.59 ± .31 | 1.67 ± .41 | – | 1.36 ± .20 | 1.30 ± .16 | – |
| Posterior cingulate | 1.82 ± .31 | 1.74 ± .36 | .021 | 1.55 ± .27 | 1.36 ± .14 | .005 |
| Precuneus | 1.56 ± .30 | 1.56 ± .36 | – | 1.20 ± .14 | 1.14 ± .09 | – |