Figure 3.

Neurons develop their connectivity in order to reach a homeostatic set-point ϵ of intracellular calcium. The figure shows the firing rates attained for different set-point values of calcium. For each calcium concentration, the firing rates of all neurons were pooled from four different simulations recorded over the last 20,000 ms. The central mark of each box is the median firing rate; boxes represent the 25th and 75th percentiles; the whiskers extend to the most extreme data points not considered “outliers”; and “outliers” are plotted individually (which show up here as thick bold lines). An “outlier” is a value that is more than 1.5 times the interquartile range away from the top or bottom of the box. The firing rate is proportional to ϵ by a factor of 100. For this set of simulations lower external inputs I^ext with mean 2 mVms⁻¹ were used.