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. 2014 Apr 7;211(4):685–700. doi: 10.1084/jem.20131343

Figure 10.

Figure 10.

S1PR1 overexpression rescues T cell egress in dynamin 2–deficient mice. (A and B) CD69 surface expression on mature CD4 SP thymocytes from Dnm2 HET, S1PR1 TG Dnm2 HET, Dnm2 KO, and S1PR1 TG Dnm2 KO mice (n = 6–9). (C and D) Flow cytometric analysis of CD4 SP thymocytes (C) and numbers of mature CD4 SP thymocytes (D) from Dnm2 HET, S1PR1 TG Dnm2 HET, Dnm2 KO, and S1PR1 TG Dnm2 KO mice (n = 9–12). All error bars represent SEM. *, P < 0.05; **, P < 0.01; ***, P < 0.001 by one-way ANOVA, Tukey’s post-test. Results are representative of or combined from two (A and B) or three (C and D) experiments.