Skip to main content
. 2014 Jan 24;21(5):797–810. doi: 10.1038/cdd.2014.3

Figure 3.

Figure 3

Cell-surface GRP78 sensitizes cells to ISM-induced apoptosis. (a) GRP78 levels in the plasma membrane fraction of HUVEC and LS174T cells. Equal amount of plasma membrane proteins were loaded as shown in the Coomassie blue-stained gel. (b) ISM-induced significant apoptosis in HUVECs. **P<0.01, n=3. Error bars denote S.E.M. (c) LS174T cells were resistant to ISM-induced apoptosis. (d) Increasing GRP78 expression level by transient transfection progressively sensitized LS174T cells to ISM-induced apoptosis dose dependently