Table 1.
Putative Mn transporters referenced in the text.
| Transporter | Tissue expression | Subcellular localization | Transcript response to Mn deficiency | Transcript response to Mn toxicity | Other proposed substrates | References |
|---|---|---|---|---|---|---|
| NRAMP FAMILY | ||||||
| AtNRAMP1 | Root (all tissues) > shoot | PM | Up in root | - - | Fe, Cd | Curie et al., 2000; Thomine et al., 2000; Cailliatte et al., 2010 |
| AtNRAMP3 | Shoot and root vasculature, developing seed | VM | None | - - | Fe, Cd | Thomine et al., 2000 |
| AtNRAMP4 | Shoot vasculature > root vasculature, developing seed | VM | None | - - | Fe, Zn, Cd | Thomine et al., 2000 |
| OsNRAMP3 | Nodes > root and leaf vasculature, panicle, husk, flower | PM | None | None (PTM) | Yamaji et al., 2013 | |
| OsNRAMP5 | Root exodermis and endodermis | PM | None | – | Cd | Ishimaru et al., 2012; Sasaki et al., 2012 |
| DMTI | Root, leaf, stems | PM/peri-bacteroid membrane | - - | - - | Fe, Zn, Cu | Kaiser et al., 2003 |
| LeNRAMP1 | Root | VM | - - | - - | Bereczky et al., 2003 | |
| LeNRAMP3 | Root > shoot | VM | - - | - - | Bereczky et al., 2003 | |
| YSL FAMILY | ||||||
| AtYSL4 | Shoot, silique, root, flower, developing seed | VM/EM/CM | None | - - | Ni, Fe** | Conte et al., 2013; Divol et al., 2013 |
| AtYSL6 | Shoot, flower, silique, developing seed | VM/EM/CM | None | - - | Ni, Fe** | Conte et al., 2013; Divol et al., 2013 |
| OsYSL2 | Leaf and leaf sheath phloem, root phloem, developing seed | PM | None | - - | Fe | Koike et al., 2004 |
| OsYSL6 | Root, shoot | Un-determined | None | - - | - - | Sasaki et al., 2011 |
| ZmYS1 | Root epidermis, leaf mesophyll | PM | - - | - - | Fe, Zn, Cu, Ni, Cd | Roberts et al., 2004; Schaaf et al., 2004; Ueno et al., 2009 |
| ZIP FAMILY | ||||||
| AtIRT1 | Root epidermis, flower | PM | None | - - | Fe, Zn, Cu, Cd, Co | Eide et al., 1996; Korshunova et al., 1999; Vert et al., 2002 |
| HvIRT1 | Root | PM, ER | None | - - | Fe, Zn | Pedas et al., 2008 |
| PsIRT1 | Root | PM | - - | - - | Fe, Zn, Cd | Cohen et al., 2004 |
| LeIRT1 | Root, flowers | - - | - - | - - | Fe, Zn, Cd | Eckhardt et al., 2001 |
| LeIRT2 | Root | - - | - - | - - | Fe, Zn, Cd | Eckhardt et al., 2001 |
| AtZIP1 | Root vasculature > shoot vasculature | VM | Up in shoot | - - | Zn | Milner et al., 2013 |
| AtZIP2 | Root vasculature > shoot vasculature | PM | Down in shoot | - - | Zn | Milner et al., 2013 |
| AtZIP5 | Root > shoot | - - | - - | - - | Milner et al., 2013 | |
| AtZIP6 | Root > shoot | - - | - - | - - | Milner et al., 2013 | |
| AtZIP7 | Shoot > root | - - | - - | - - | Zn, Fe | Milner et al., 2013 |
| AtZIP9 | Root, shoot | - - | - - | - - | Milner et al., 2013 | |
| MtZIP4 | Leaf, root* | MM (predicted) | Down in leaf | - - | Lopez-Millan et al., 2004 | |
| MtZIP7 | Leaf | PM (predicted) | None | - - | Lopez-Millan et al., 2004 | |
| CAX FAMILY | ||||||
| AtCAX2 | Root, shoot and flower vasculature, fruit, stem | VM | - - | None | Ca, Cd, Zn | Hirschi et al., 2000; Schaaf et al., 2002; Shigaki et al., 2003; Pittman et al., 2004; Edmond et al., 2009 |
| AtCAX4 | Root, leaf, stem, flower, silique | VM | - - | Up | Cd | Cheng et al., 2002 |
| AtCAX5 | Root, stem, fruit, flower, leaf | VM | - - | Up | Edmond et al., 2009 | |
| OsCAX1a | Root, shoot, flower | - - | - - | - - | Ca | Kamiya and Maeshima, 2004; Kamiya et al., 2005 |
| OsCAX3 | Root, shoot, flower | - - | - - | - - | Ca | Kamiya and Maeshima, 2004; Kamiya et al., 2005 |
| LeCAX2 | Leaf, fruit | - - | - - | - - | Ca | Edmond et al., 2009 |
| HvCAX2 | Root, shoot, seed | - - | - - | None | Ca | Edmond et al., 2009 |
| CCX FAMILY | ||||||
| AtCCX3 | Flowers, stem, leaf, root | VM, EM | - - | Up in root and flowers | Na, K | Morris et al., 2008 |
| CDF/MTP FAMILY | ||||||
| AtMTP11 | Leaf hydathodes, guard cells, root tip | Golgi/PVC | - - | None | Delhaize et al., 2007; Peiter et al., 2007 | |
| OsMTP8.1 | Shoot | VM | None | Up in shoot | Chen et al., 2013 | |
| ShMTP8 | - - | Internal organelle | - - | - - | - - | Delhaize et al., 2003 |
| PtMTP11.1 | - - | GLC | - - | - - | Peiter et al., 2007 | |
| PtMTP11.2 | - - | GLC | - - | - - | Peiter et al., 2007 | |
| BmMTP10 | Root, shoot | Golgi | - - | Up in root and shoot | Erbasol et al., 2013 | |
| BmMTP11 | Root, shoot | Golgi | - - | None | Erbasol et al., 2013 | |
| P-type ATPase FAMILY | ||||||
| AtECA1 | Root vasculature, flower, leaf vasculature, stem, silique | ER | - - | - - | Ca, Zn, Ni | Wu et al., 2002 |
| AtECA3 | Root vasculature and tip, Leaf vasculature, hydathodes, guard cells, flower, stem, silique | Golgi/EM | None | - - | Ca | Mills et al., 2008 |
| LeLCA1 | - - | - - | - - | - - | Ca | Johnson et al., 2009 |
| VIT/CCC1-LIKE FAMILY | ||||||
| AtVIT1 | Developing seed, vasculature | VM | - - | - - | Fe | Kim et al., 2006 |
| OsVIT1 | Leaf > root, stem, panicle, embryo | VM | - - | - - | Fe, Zn | Zhang et al., 2012 |
| OsVIT2 | Leaf > root, stem, panicle, embryo | VM | - - | - - | Fe, Zn | Zhang et al., 2012 |
*
Only during Zn deficiency.
**
Not observed by Conte et al. (2013). At, Arabidopsis thaliana; Hv, Hordeum vulgare; Ps, Pisum sativum; Le, Lycopersicon esculentum (Solanum lycopersicum); Mt, truncatula; Os, Oryza sativa; Zm, Zea mays; Bm, Beta vulgaris; PM, Plasma Membrane; ER, Endoplasmic Reticulum; VM, Vacuolar Membrane; MM, Mitochondrial Membrane; EM, Endomembrane Compartment; PVC, Pre-Vacuolar Compartment; GLC, Golgi-Like Compartment; PTM, Post-Translational Modification; - -, not tested.