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Hormone therapy effects on incidence of expression and intensity of IHC staining for RANK and RANKL. (a) Incidence score for RANK or RANKL immunohistochemical (IHC) positivity in each group. (b) Mean composite IHC score +/− standard error of the mean in each treatment group. Letters indicate significant differences versus control (P < 0.05a, P < 0.01b, P < 0.001c) or conjugated equine estrogens (CEE) (P < 0.001d) groups.
