Table 1.
Frequencies of DNA methylation in the cancer tissue samples
| Loci ID | Samples available a | Methylation-negative, n (%) | Low methylation, n (%) b | Heterogeneous methylation, n (%) | Full methylation, n (%) | Both alleles present, n (%) |
|---|---|---|---|---|---|---|
|
TITF1 |
220 |
0 (0.0) |
38 (17.3) |
0 |
145 (65.9) |
37 (16.8) |
|
HOXB13 |
239 |
18 (7.5) |
20 (8.4) |
0 |
23 (9.6) |
178 (74.5) |
|
NR2E1 |
164 |
15 (9.1) |
14 (8.5) |
18 (11.0) |
89 (54.3) |
28 (17.1) |
|
HTR1B |
162 |
28 (17.3) |
68 (42.0) |
20 (12.3) |
4 (2.5) |
42 (25.9) |
|
HMX2 |
187 |
9 (4.8) |
1 (0.5) |
13 (7.0) |
164 (87.7) |
0 |
|
BC008699 |
261 |
4 (1.5) |
4 (1.5) |
26 (10.0) |
206 (78.9) |
21 (8.0) |
|
SLC38A4 |
234 |
0 |
16 (6.8) |
93 (39.7) |
80 (34.2) |
45 (19.2) |
|
FLJ32447 |
264 |
0 |
28 (10.6) |
191 (72.3) |
48 (18.2) |
0 |
|
WT1 |
218 |
44 (20.2) |
0 |
178 (81.7) |
21 (9.6) |
0 |
|
TMEM132D |
218 |
6 (2.8) |
21 (9.6) |
154 (70.6) |
16 (7.3) |
21 (9.6) |
|
NKX2-3 |
169 |
0 |
16 (9.5) |
108 (63.9) |
38 (22.5) |
7 (4.1) |
|
GHSR |
260 |
56 (21.5) |
24 (9.2) |
180 (69.2) |
0 |
0 |
|
ONECUT |
243 |
0 |
16 (9.5) |
134 (55.1) |
63 (25.9) |
30 (12.3) |
|
LHX1 |
243 |
0 |
28 (11.5) |
145 (59.7) |
41 (16.9) |
29 (11.9) |
|
SIX6 |
246 |
5 (2.0) |
11 (4.5) |
173 (70.3) |
55 (22.4) |
2 (0.8) |
|
CA10 |
230 |
21 (9.1) |
48 (20.9) |
137 (59.6) |
24 (10.4) |
0 |
|
CHR |
252 |
0 |
44 (17.5) |
192 (76.2) |
16 (6.3) |
0 |
|
POU4F |
255 |
10 (3.9) |
6 (2.4) |
195 (76.5) |
44 (17.3) |
0 |
| PHOX2B | 256 | 0 | 3 (1.2) | 199 (77.7) | 53 (20.7) | 1 (0.4) |
aVariable numbers of the samples are reported because of clinical sample limitations. bLow methylation is referred to as methylation similar to the methylation observed in control samples.