Table 2.
Pre-donation comparison of marrow and PBSC donors.
| Study Variable | Marrow (n=161) |
PBSC (n=170) |
Test Statistic (t or odds-ratio) |
p-value |
|---|---|---|---|---|
| Sociodemographic | ||||
| age (mean, sd) | 33.6 (9.18) | 35.1 (10.29) | -1.45 | 0.148 |
| % women | 34 | 34 | 1.03 (0.65-1.62) | 0.912 |
| % married | 63 | 53 | 0.67 (0.43-1.04) | 0.071 |
| % ≥ Bachelor's degree | 46 | 53 | 1.32 (0.86-2.04) | 0.204 |
| % employed | 93 | 91 | 1.32 (0.59-2.97) | 0.501 |
| Race | ||||
| % Caucasian/White | 86 | 83 | ||
| % Hispanic | 6 | 8 | ||
| % African American | 4 | 4 | ||
| % Asian American | 1 | 2 | ||
| % Other | 2 | 2 | ||
| Physical Status | ||||
| Overall physical status | ||||
| SF-8 physical health (mean, sd) (29-68)† | 56.47 (3.71) | 55.86 (4.79) | 0.78 | 0.436 |
| Current physical symptoms | ||||
| % tiredness | 49 | 52 | 1.10 (0.70-1.74) | 0.685 |
| % muscle aches | 17 | 24 | 1.54 (0.86-2.74) | 0.145 |
| % problems sleeping | 15 | 16 | 1.07 (0.57-2.00) | 0.845 |
| % bone pain | 6 | 8 | 1.49 (0.59-3.76) | 0.397 |
| % light headedness | 6 | 5 | 0.85 (0.32-2.27) | 0.747 |
| % difficulty walking | 4 | 4 | 0.97 (0.30-3.07) | 0.952 |
| % bleeding | 7 | 3 | 0.37 (0.11-1.21) | 0.087 |
| % nausea or vomiting | 1 | 4 | 6.00 (0.71-50.47) | 0.062 |
| % infection | 3 | 0 | 0.48 (0.43-0.55) | 0.041* |
| % chills | 2 | 2 | 0.97 (0.19-4.87) | 0.966 |
| % fainting | 1 | 1 | 0.97 (0.06-15.60) | 0.981 |
| Current physical symptoms | ||||
| Psychological Status | ||||
| Overall psychological status | ||||
| SF-8 mental health (mean, sd) (28-69) | 55.68 (4.83) | 55.12 (5.37) | 0.94 | 0.350 |
| Profile of mood states (POMS) | ||||
| depression (mean, sd) (0-4) | 0.10 (0.29) | 0.11 (0.24) | -0.28 | 0.784 |
| vitality (mean, sd) (0-4) | 2.40 (0.82) | 2.46 (0.67) | -0.60 | 0.548 |
| confusion (mean, sd) (0-4) | 0.23 (0.34) | 0.31 (0.40) | -2.04 | 0.043* |
| tension (mean, sd) (0-4) | 0.44 (0.51) | 0.45 (0.47) | -0.11 | 0.911 |
| anger (mean, sd) (0-4) | 0.22 (0.38) | 0.22 (0.32) | 0.06 | 0.951 |
| fatigue (mean, sd) (0-4) | 0.46 (0.61) | 0.55 (0.62) | -1.36 | 0.174 |
| total distress (mean, sd) (0-24) | 4.21 (1.91) | 4.19 (1.91) | 0.07 | 0.941 |
| Donation-related | ||||
| Interaction with others | ||||
| % consulted family/friends | 58 | 56 | 1.08 (0.68-1.72) | 0.738 |
| % consulted professionals | 29 | 35 | 0.75 (0.46-1.22) | 0.242 |
| % encouraged to donate | 26 | 30 | 0.80 (0.48-1.33) | 0.390 |
| % discouraged from donating | 26 | 27 | 0.91 (0.54-1.53) | 0.727 |
| Medical concerns | ||||
| % pain | 58 | 55 | 0.89 (0.56-1.40) | 0.604 |
| % anesthesia | 35 | 33 | 0.91 (0.56-1.48) | 0.709 |
| % damage health | 26 | 39 | 1.81 (1.10-2.97) | 0.018* |
| % use of needles | 13 | 16 | 1.33 (0.69-2.58) | 0.391 |
| Work/family concerns | ||||
| % family will worry | 56 | 49 | 0.78 (0.49-1.23) | 0.286 |
| % missing work/school | 43 | 41 | 0.92 (0.58-1.46) | 0.714 |
| % reimbursement for missed work | 19 | 19 | 1.00 (0.56-1.80) | 0.993 |
| % missing family activities | 15 | 15 | 1.06 (0.56-2.02) | 0.857 |
| % child/family care | 15 | 11 | 0.66 (0.33-1.32) | 0.239 |
| Other concerns | ||||
| % patient's chances are low | 43 | 38 | 0.83 (0.52-1.33) | 0.443 |
| % payment for medical treatment | 18 | 14 | 0.74 (0.40-1.38) | 0.343 |
| % transportation to donor center | 14 | 12 | 0.85 (0.43-1.67) | 0.629 |
| % against religious beliefs | 0 | 1 | 0.51 (0.45-0.57) | 0.164 |
| Overall health concerns | ||||
| % worry about longer-term health impact of donation | 63 | 66 | 1.13 (0.70-1.82) | 0.615 |
| % worry will never feel physically 100% again | 29 | 27 | 0.89 (0.54-1.49) | 0.658 |
| Preparation | ||||
| % feel very well informed | 84 | 79 | 0.70 (0.39-1.27) | 0.239 |
| % feel totally prepared | 85 | 75 | 0.55 (0.31-0.99) | 0.045* |
| % need much more information | 20 | 30 | 1.70 (0.99-2.91) | 0.051* |
| Satisfaction with donation decision | ||||
| % extremely satisfied with decision | 90 | 91 | 1.05 (0.48-2.30) | 0.894 |
| % would definitely volunteer again | 92 | 91 | 0.80 (0.35-1.82) | 0.590 |
| Clinical | ||||
| Weight (mean, sd) | 88.12 kg (18.64) | 85.07 kg (17.33) | 1.52 | 0.128 |
| Height (mean, sd) | 174.48 cm (9.15) | 173.92 cm (10.26) | 0.52 | 0.607 |
*
p ≤ .05;
**
p ≤ .01;
***
p ≤ .001
†
response range