Table 3.

48 hours post-donation comparison of marrow and PBSC donors.

Study Variable	Marrow (n=131)	PBSC (n=142)	Test Statistic (t or odds ratio)	p-value
Physical Status
Overall physical status
SF-8 physical health (mean, sd) (29-68)†	35.38 (9.75)	43.37 (9.75)	-6.59	0.000***
Current physical symptoms
% tiredness	92	92	0.98 (0.40-2.40)	0.972
% muscle aches	75	56	0.42 (0.25-0.71)	0.421
% problems sleeping	50	39	0.66 (0.41-1.07)	0.091
% bone pain	58	60	1.09 (0.67-1.77)	0.717
% light headedness	50	34	0.50 (0.31-0.82)	0.006**
% pain where needles inserted	83	55	0.25 (0.14-0.44)	0.000***
% difficulty walking	87	39	0.10 (0.05-0.18)	0.000***
% bleeding	41	10	0.16 (0.08-0.30)	0.000***
% nausea or vomiting	28	25	0.86 (0.51-1.48)	0.590
% infection	0	0	--	--
% chills	20	9	0.41 (0.20-0.83)	0.012*
% fainting	3	0	0.47 (0.42-0.54)	0.036*
Current pain1
pain index (mean, sd) (0-10)	4.23 (1.86)	3.84(1.94)	1.68	0.094
average pain (mean, sd) (0-10)	4.04 (1.98)	3.63(2.00)	1.69	0.093
worst pain (mean, sd) (0-10)	5.55 (2.45)	4.80(2.26)	2.60	0.009**
time with pain (mean, sd) (0-10)	4.77 (2.42)	4.57(2.58)	0.66	0.513
interfered with sleep (mean, sd) (0-10)	2.53 (2.40)	2.35(2.34)	0.62	0.535
Psychological Status
Overall psychological status
SF-8 mental health (mean, sd) (28-69)	55.40 (7.24)	52.23 (6.24)	3.85	0.000***
Profile of mood states (POMS)
depression (mean, sd) (0-4)	0.10 (0.42)	0.12 (0.24)	-0.61	0.541
vitality (mean, sd) (0-4)	1.23 (0.93)	1.46 (0.88)	-2.12	0.035*
confusion (mean, sd) (0-4)	0.26 (0.69)	0.25 (0.42)	0.13	0.900
tension (mean, sd) (0-4)	0.46 (0.69)	0.47 (0.51)	-0.19	0.848
anger (mean, sd) (0-4)	0.12 (0.48)	0.14 (0.25)	-0.50	0.615
fatigue (mean, sd) (0-4)	1.31 (1.02)	1.23 (0.91)	0.69	0.491
total distress (mean, sd) (0-24)	5.01 (2.75)	4.75 (2.28)	0.85	0.396
Donation-related
Donation experience
% donation physically stressful	76	75	0.91 (0.53-1.59)	0.746
% donation emotionally stressful	55	58	1.12 (0.69-1.81)	0.643
Health concerns
% worry about longer-term health impact of donation	55	58	1.10 (0.68-1.78)	0.695
% worry will never feel physically 100% again	27	32	1.30 (0.75-2.13)	0.389
Social impact
% leisure/recreation affected	87	51	6.46 (3.52-11.86)	0.000***
% work/school affected	75	70	1.29 (0.75-2.20)	0.359
% transportation arrangements	58	47	1.55 (0.96-2.50)	0.073
% child care arrangements	28	16	2.04 (1.13-3.66)	0.016*
% financial arrangements	18	13	1.55 (0.80-3.00)	0.197
% home care help	7	4	1.67 (0.58-4.83)	0.338
Satisfaction with donation decision
% extremely satisfied with decision	92	92	0.90 (0.37-2.15)	0.804
% would definitely donate again	79	78	0.94 (0.53-1.68)	0.843
% would strongly encourage others	82	82	1.00 (0.53-1.86)	0.992
% feel a lot like a better person	76	76	1.02 (0.58-1.78)	0.958
% feel very proud	63	65	1.06 (0.65-1.75)	0.806
% made life much more meaningful	48	35	0.58 (0.35-0.94)	0.026*
Recipient-related
% know health status of recipient	7	10	0.67 (0.28-1.60)	0.365
% think about recipient ≥ once/day	79	78	0.92 (0.52-1.65)	0.784
% have special bond with recipient	82	79	0.80 (0.43-1.46)	0.457
% very/pretty worried about recipient	66	61	0.80 (0.49-1.32)	0.385
Clinical
% adverse event	15	16	1.12 (0.61-2.06)	0.705
% serious adverse event	6	2	0.30 (0.08-1.13)	0.061

^*p ≤ .05;

^**p ≤ .01;

^***p ≤ .001

^†response range

¹For PBSC donors, pain was assessed on the 4^th day of rhGCSF administration. For BM donors, pain was assessed 48hours post-donation.