Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2014 Jan 23;16(1):R20. doi: 10.1186/ar4448

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2014 Dominguez-Gutierrez et al.; licensee BioMed Central Ltd.

This is an open access article distributed under the terms of the Creative Commons Attribution License ( http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

PMC Copyright notice

Correlation of IFN score, STAT1, ADAR, CCL2, CXCL10, and miR-146a levels to anti-double-strandard DNA (dsDNA) autoantibodies. (A) Systemic lupus erythematosus disease activity (SLEDAI) scores were significantly higher in anti-dsDNA(+) than anti-dsDNA(−) patient visits. (B, C) C3 and C4 were significantly lower in anti-dsDNA(+) than in anti-dsDNA(−) patients. (D) IFN score, (E) STAT1, (F) ADAR, (G) CCL2, and (H) CXCL10 were significantly elevated in SLE patient visits compared to healthy donors (HD), but no statistical differences were detected between anti-dsDNA(+) and anti-dsDNA(−) patients for IFN score, ADAR, or CXCL10. (I-K) TNFα, pri-miR-146a, and miR-146a did not show any significant difference among the groups. STAT, signal transducers and activators of transcription; ADAR, adenosine deaminase acting on RNA; CCL2, C-C motif chemokine ligand 2; CXCL10, C-X-C motif chemokine 10.