Table 2.
Immunohistochemistry characteristics according to ACPA status
| Synovial cells | Total number = 83 | ACPA positive number = 64 | ACPA negative number = 19 | P value |
|---|---|---|---|---|
| CD3/mm2 (Median, IQR 25 to 75) |
509.90(210.7–821.6) n = 70 |
514.10 (198.9–821.6) N = 54 |
509.30 (233.8–898.2) n = 16 |
0.823 |
| CD20/mm2 (Median, IQR 25 to 75) |
126.52 (30.3–242.6) n = 70 |
117.90 (26.6–235.4) n = 54 |
162.73 (42.2–315) n = 16 |
0.386 |
| CD20 cell grade 3 follicles (Median, IQR 25 to 75) |
0 (0–2.7) n = 72 |
0 (0–2) n = 55 |
2.0 (0–3.5) n = 17 |
0.221 |
| CD68L/mm2 (Median, IQR 25 to 75) |
293.34 (94.2–453.4) n = 63 |
305.59 (94.2–438.5) n = 47 |
204.74 (93.5–532.2) n = 16 |
0.813 |
| CD68SL/mm2 (Median, IQR 25 to 75) |
677.17 (3.1–1665.5) n = 63 |
738.50 (379.3–2016.7) n = 47 |
526.74 (271.5–874.9) n = 16 |
0.138 |
| CD15/mm2 (Median, IQR 25 to 75) |
58.46 (10–204.4) n = 49 |
71.90 (9.0–445.4) n = 35 |
35.74 (9.9–88) n = 14 |
0.278 |
| CD117/mm2 (Median, IQR 25 to 75) |
40.26 (20.8–55) n = 51 |
39.27 (21.2–54.5) n = 37 |
42.81 (19.1–75.6) n = 14 |
0.473 |
| CD31/34 (Median, IQR 25 to 75) |
46.31 (37.4–64.1) n = 44 |
53.66 (36.8–68.8) n = 31 |
43.56 (34–63) n = 13 |
0.425 |
| LN (%) | 40.80 | 39.50 | 58.80 | 0.119 |
ACPA, anti-citrullinated peptide/protein antibodies; IQR, interquatile range; LN, lymphoid neogenesis; n, number.