Table 3.
Targeted qPCR analysis of mammary glands after 3, 4, or 10 weeks on HFD versus LFD
|
Inflammation PCR array |
Fold change HFD versus LFD |
|||
|---|---|---|---|---|
| Symbol | Description | 3 wks MG | 4 wks MG | 10 wks MG |
|
Ccl24 |
Chemokine (C-C motif) ligand 24 |
2.7 |
- |
- |
|
Ccl3 |
Chemokine (C-C motif) ligand 3 |
2.3 |
- |
- |
|
Il4 |
Interleukin 4 |
2.2 |
- |
- |
|
Il5ra |
Interleukin 5 receptor, alpha |
3.0 |
- |
- |
|
RANKL |
Receptor activator of nuclear factor kappa-B ligand |
- |
17 |
- |
|
Ccl1 |
Chemokine (C-C motif) ligand 1 |
- |
- |
4.5 |
|
Ccl17 |
Chemokine (C-C motif) ligand 17 |
- |
- |
3.2 |
|
Ccl19 |
Chemokine (C-C motif) ligand 19 |
- |
- |
7.5 |
|
Ccl20 |
Chemokine (C-C motif) ligand 20 |
- |
- |
5.2 |
|
Ccl22 |
Chemokine (C-C motif) ligand 22 |
- |
- |
7.6 |
|
Il1b |
Interleukin 1 beta |
- |
- |
2.1 |
|
Il2rb |
Interleukin 2 receptor, beta chain |
- |
- |
2.7 |
|
Cxcr2 |
Chemokine (C-X-C motif) receptor 2 |
- |
- |
4.3 |
|
Lta |
Lymphotoxin A |
- |
- |
3.2 |
| Xcr1 | Chemokine (C motif) receptor 1 | - | - | 2.5 |
N = 3 high fat diet (HFD) mice, n = 3 low fat diet (LFD) mice; n = 3 mice with early developing tumors while on HFD (HFD-E), n = 3 LFD mice with tumors. P ≤0.05 for all genes listed.