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. 2013 Oct 25;15(5):R100. doi: 10.1186/bcr3561

Table 5.

Targeted qPCR analysis comparing HFD-E tumors with LFD tumors

Breast cancer genes
HFD-E versus LFD tumor
Symbol Description Fold change
Brca2
Breast cancer 2
1.8
Ccnd2
Cyclin D2
3.5
Igf1r
Insulin-like growth factor I receptor
3.5
Slit2
Slit homolog 2 (Drosophila)
2.9
Trp53
Transformation related protein 53
1.6
Krt18
Keratin 18
-3.8
Krt8
Keratin 8
-4.7
Cancer pathway finder genes
HFD-E versus LFD tumor
Apaf1
Apoptotic peptidase activating factor 1
1.8
Brca1
Breast cancer 1
1.8
Ctnnb1
Catenin (cadherin associated protein), beta 1
1.8
Tert Telomerase reverse transcriptase 1.9

N = 3 mice with early developing tumors while on high fat diet (HFD-E), n = 3 low fat diet (LFD) mice with tumors. P ≤0.05 for all genes listed.